Insights into epigenetic patterns in mammalian early embryos

Abstract Mammalian fertilization begins with the fusion of two specialized gametes, followed by major epigenetic remodeling leading to the formation of a totipotent embryo. During the development of the pre-implantation embryo, precise reprogramming progress is a prerequisite for avoiding developmen...

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Bibliographic Details
Main Authors: Ruimin Xu, Chong Li, Xiaoyu Liu, Shaorong Gao
Format: Article
Language:English
Published: SpringerOpen 2020-07-01
Series:Protein & Cell
Subjects:
Online Access:https://doi.org/10.1007/s13238-020-00757-z