Structural Insights into the Mammalian Late-Stage Initiation Complexes

Summary: In higher eukaryotes, the mRNA sequence in the direct vicinity of the start codon, called the Kozak sequence (CRCCaugG, where R is a purine), is known to influence the rate of the initiation process. However, the molecular basis underlying its role remains poorly understood. Here, we presen...

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Bibliographic Details
Main Authors: Angelita Simonetti, Ewelina Guca, Anthony Bochler, Lauriane Kuhn, Yaser Hashem
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720303867