Synonymous point mutation of gtfB gene caused by therapeutic X-rays exposure reduced the biofilm formation and cariogenic abilities of Streptococcus mutans

Abstract Background The shift of oral microbiota is a critical factor of radiation caries in head and neck cancer patients after the radiotherapy. However, the direct effects of irradiation on the genome and virulence of cariogenic bacteria are poorly described. Here we investigated the genomic muta...

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Bibliographic Details
Main Authors: Zheng Wang, Yujie Zhou, Qi Han, Xingchen Ye, Yanyan Chen, Yan Sun, Yaqi Liu, Jing Zou, Guohai Qi, Xuedong Zhou, Lei Cheng, Biao Ren
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Cell & Bioscience
Online Access:https://doi.org/10.1186/s13578-021-00608-2