An untargeted multi-technique metabolomics approach to studying intracellular metabolites of HepG2 cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin

<p>Abstract</p> <p>Background</p> <p><it>In vitro </it>cell systems together with omics methods represent promising alternatives to conventional animal models for toxicity testing. Transcriptomic and proteomic approaches have been widely applied <it>in...

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Bibliographic Details
Main Authors: van Delft Joost, Jennen Danyel, Kleinjans Jos, Peijnenburg Ad, Ruiz-Aracama Ainhoa, Hellfrisch Caroline, Lommen Arjen
Format: Article
Language:English
Published: BMC 2011-05-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/12/251