Gold(III) Pyridine-Benzimidazole Complexes as Aquaglyceroporin Inhibitors and Antiproliferative Agents

Gold(III) Pyridine-Benzimidazole Complexes as Aquaglyceroporin Inhibitors and Antiproliferative Agents

Gold compounds have been proven to be novel and versatile tools for biological applications, including as anticancer agents. Recently, we explored the potential of Au(III) complexes with bi-dentate N-donor ligands as inhibitors of the membrane water and glycerol channels aquaporins (AQPs), involved...

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Bibliographic Details
Main Authors: Brech Aikman, Margot N. Wenzel, Andreia F. Mósca, Andreia de Almeida, Wim T. Klooster, Simon J. Coles, Graça Soveral, Angela Casini
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Inorganics
Subjects:
Gold(III) complexes
pyridine benzimidazole
aquaporins
cancer
stopped-flow spectroscopy
antiproliferative activity
Online Access:https://www.mdpi.com/2304-6740/6/4/123

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https://www.mdpi.com/2304-6740/6/4/123

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