Potent immunomodulation and angiogenic effects of mesenchymal stem cells versus cardiomyocytes derived from pluripotent stem cells for treatment of heart failure

Abstract Background Optimal cell type as cell-based therapies for heart failure (HF) remains unclear. We sought to compare the safety and efficacy of direct intramyocardial transplantation of human embryonic stem cell-derived cardiomyocytes (hESC-CMs) and human induced pluripotent stem cell-derived...

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Bibliographic Details
Main Authors: Songyan Liao, Yuelin Zhang, Sherwin Ting, Zhe Zhen, Fan Luo, Ziyi Zhu, Yu Jiang, Sijia Sun, Wing-Hon Lai, Qizhou Lian, Hung-Fat Tse
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13287-019-1183-3