New analogues of 13-hydroxyocatdecadienoic acid and 12-hydroxyeicosatetraenoic acid block human blood platelet aggregation and cyclooxygenase-1 activity
<p>Abstract</p> <p>Background</p> <p>Thromboxane A<sub>2</sub> is derived from arachidonic acid through the action of cyclooxygenases and thromboxane synthase. It is mainly formed in blood platelets upon activation and plays an important role in aggregation....
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2012-12-01
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| Series: | Chemistry Central Journal |
| Subjects: | |
| Online Access: | http://journal.chemistrycentral.com/content/6/1/152 |