N-Alkoxyphenylhydroxynaphthalenecarboxamides and Their Antimycobacterial Activity

N-Alkoxyphenylhydroxynaphthalenecarboxamides and Their Antimycobacterial Activity

A series of nineteen N-(alkoxyphenyl)-2-hydroxynaphthalene-1-carboxamides and a series of their nineteen positional isomers N-(alkoxyphenyl)-1-hydroxynaphthalene-2-carboxamides were prepared and characterized. Primary in vitro screening of all the synthesized compounds was performed against Mycobact...

Full description

Bibliographic Details
Main Authors: Tomas Gonec, Sarka Pospisilova, Tereza Kauerova, Jiri Kos, Jana Dohanosova, Michal Oravec, Peter Kollar, Aidan Coffey, Tibor Liptaj, Alois Cizek, Josef Jampilek
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Series:Molecules
Subjects:
hydroxynaphthalenecarboxamides
in vitro antimycobacterial activity
MTT assay
lipophilicity
structure-activity relationships
Online Access:http://www.mdpi.com/1420-3049/21/8/1068

Internet

http://www.mdpi.com/1420-3049/21/8/1068

Similar Items