Codon Optimization and Chaperone Assisted Solubilization of Recombinant Human Prethrombin-2 Expressed in Escherichia coli

Codon Optimization and Chaperone Assisted Solubilization of Recombinant Human Prethrombin-2 Expressed in Escherichia coli

Prethrombin-2 (PT2) is a thrombin precursor, which plays a role in the conversion of fibrinogen into fibrin during blood clotting process. Previous study reported that the expression of human prothrombin-2 (rhPT2) in Escherichia coli formed inclusion bodies. The aim of this study was to establish a...

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Bibliographic Details
Main Authors: SARONOM SILABAN, IMAN PERMANA MAKSUM, SHABARNI GHAFFAR, KHOMAINI HASAN, SUTARYA ENUS, TOTO SUBROTO, SOETIJOSO SOEMITRO
Format: Article
Language:English
Published: Indonesian Society for Microbiology 2015-03-01
Series:Microbiology Indonesia
Subjects:
thrombin
prethrombin-2
inclusion bodies
chaperon
E. coli
Online Access:https://jurnal.permi.or.id/index.php/mionline/article/view/306

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https://jurnal.permi.or.id/index.php/mionline/article/view/306

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