Antibacterial effects of Traditional Chinese Medicine monomer against Streptococcus pneumoniae via inhibiting pneumococcal histidine kinase (VicK)

Antibacterial effects of Traditional Chinese Medicine monomer against Streptococcus pneumoniae via inhibiting pneumococcal histidine kinase (VicK)

Two-component systems (TCSs) have the potential to be an effective target of the antimicrobials. VicK/VicR is one of TCSs in S. pneumoniae, which is essential for pneumococcal survival. We have previously obtained serveal Traditional Chinese Medicine monomers using a computer-based screening. In thi...

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Bibliographic Details
Main Authors: Shuai eZhang, Jianmin eWang, Wenchun eXu, Yusi eLiu, Wei eWang, Kaifeng eWu, Zhe eWang, Xuemei eZhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-05-01
Series:Frontiers in Microbiology
Subjects:
antimicrobial
Histidine kinase
S.pneumoniae
Traditional Chinese medicine monomer
Vick protein
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00479/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00479/full

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