HigB Reciprocally Controls Biofilm Formation and the Expression of Type III Secretion System Genes through Influencing the Intracellular c-di-GMP Level in <i>Pseudomonas aeruginosa</i>

HigB Reciprocally Controls Biofilm Formation and the Expression of Type III Secretion System Genes through Influencing the Intracellular c-di-GMP Level in <i>Pseudomonas aeruginosa</i>

Toxin-antitoxin (TA) systems play important roles in bacteria persister formation. Increasing evidence demonstrate the roles of TA systems in regulating virulence factors in pathogenic bacteria. The toxin HigB in <i>Pseudomonas aeruginosa</i> contributes to persister formation and regula...

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Bibliographic Details
Main Authors: Yueying Zhang, Bin Xia, Mei Li, Jing Shi, Yuqing Long, Yongxin Jin, Fang Bai, Zhihui Cheng, Shouguang Jin, Weihui Wu
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Toxins
Subjects:
toxin-antitoxin system
HigB/HigA
<i>Pseudomonas aeruginosa</i>
type III secretion system
biofilm
c-di-GMP
Online Access:https://www.mdpi.com/2072-6651/10/11/424

Internet

https://www.mdpi.com/2072-6651/10/11/424

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