Dissociation of Calcium Transients and Force Development following a Change in Stimulation Frequency in Isolated Rabbit Myocardium

As the heart transitions from one exercise intensity to another, changes in cardiac output occur, which are modulated by alterations in force development and calcium handling. Although the steady-state force-calcium relationship at various heart rates is well investigated, regulation of these proces...

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Bibliographic Details
Main Authors: Kaylan M. Haizlip, Nima Milani-Nejad, Lucia Brunello, Kenneth D. Varian, Jessica L. Slabaugh, Shane D. Walton, Sandor Gyorke, Jonathan P. Davis, Brandon J. Biesiadecki, Paul M. L. Janssen
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/468548