Biologic variability of human foreskin fibroblasts in 2D and 3D culture: implications for a wound healing model

<p>Abstract</p> <p>Background</p> <p>The fibroblast-populated 3D collagen matrix is a model of tissue and healing which has been used since the 1980's. It was hypothesized that anchorage disruption of the collagen matrix would produce p53-dependent apoptosis in the...

Full description

Bibliographic Details
Main Authors: Lesiak Alex, Gums Jeremiah J, Prall Amy K, Carlson Mark A, Shostrom Valerie K
Format: Article
Language:English
Published: BMC 2009-11-01
Series:BMC Research Notes
Online Access:http://www.biomedcentral.com/1756-0500/2/229