Junction region of EWS-FLI1 fusion protein has a dominant negative effect in Ewing’s Sarcoma <it>in vitro</it>

<p>Abstract</p> <p>Background</p> <p>Ewing’s sarcoma is a malignancy characterized by a specific 11:22 chromosomal translocation which generates a novel EWS-FLI1 fusion protein functioning as an aberrant transcription factor. In the present study, we have further charac...

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Bibliographic Details
Main Authors: Jully Babu, Vijayalakshmi Ramshankar, Gopal Gopisetty, Sabitha Kesavan, Rajkumar Thangarajan
Format: Article
Language:English
Published: BMC 2012-11-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/12/513