Statistical evaluation of worst-case robust optimization intensity-modulated proton therapy plans using an exhaustive sampling approach

Abstract Purpose To assess the worst-case robust optimization IMPT plans with setup and range uncertainties and to test the hypothesis that the worst-case robust optimization strategies could cover most possible setup and range uncertainties in the real scenarios. Methods We analyzed the nominal and...

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Bibliographic Details
Main Authors: Zhiyong Yang, Heng Li, Yupeng Li, Yuting Li, Yu Chang, Qin Li, Kunyu Yang, Gang Wu, Narayan Sahoo, Falk Poenisch, Michael Gillin, X. Ronald Zhu, Xiaodong Zhang
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Radiation Oncology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13014-019-1335-8