Lipid Nanoparticles Potentiate CpG-Oligodeoxynucleotide-Based Vaccine for Influenza Virus

Current influenza vaccines are generally effective against highly similar (homologous) strains, but their effectiveness decreases markedly against antigenically mismatched (heterologous) strains. One way of developing a universal influenza vaccine with a broader spectrum of protection is to use appr...

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Bibliographic Details
Main Authors: Seiki Shirai, Meito Shibuya, Atsushi Kawai, Shigeyuki Tamiya, Lisa Munakata, Daiki Omata, Ryo Suzuki, Taiki Aoshi, Yasuo Yoshioka
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.03018/full