Circular RNA MCTP2 inhibits cisplatin resistance in gastric cancer by miR-99a-5p-mediated induction of MTMR3 expression

Circular RNA MCTP2 inhibits cisplatin resistance in gastric cancer by miR-99a-5p-mediated induction of MTMR3 expression

Abstract Background Cisplatin (CDDP) is the first-line chemotherapy for gastric cancer (GC). The poor prognosis of GC patients is partially due to the development of CDDP resistance. Circular RNAs (circRNAs) are a subclass of noncoding RNAs that function as microRNA (miRNA) sponges. The role of circ...

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Bibliographic Details
Main Authors: Guangli Sun, Zheng Li, Zhongyuan He, Weizhi Wang, Sen Wang, Xing Zhang, Jiacheng Cao, Penghui Xu, Haixiao Wang, Xiaoxu Huang, Yiwen Xia, Jialun Lv, Zhe Xuan, Tianlu Jiang, Lang Fang, Jing Yang, Diancai Zhang, Hao Xu, Zekuan Xu
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
GC
Cisplatin
CircMCTP2
miR-99a-5p
MTMR3
Online Access:http://link.springer.com/article/10.1186/s13046-020-01758-w

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http://link.springer.com/article/10.1186/s13046-020-01758-w

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