Western diet leads to aging-related tumorigenesis via activation of the inflammatory, UPR, and EMT pathways

Abstract Among the principal causative factors for the development of complications related to aging is a diet rich in fats and sugars, also known as the Western diet. This diet advocates numerous changes that might increase the susceptibility to initiate cancer and/or to create a tissue microenviro...

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Bibliographic Details
Main Authors: Ricardo Imbroisi Filho, Alan C. Ochioni, Amanda M. Esteves, João G. B. Leandro, Thainá M. Demaria, Mauro Sola-Penna, Patricia Zancan
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03929-9