Systemic Administration of Fibroblast Growth Factor 21 Improves the Recovery of Spinal Cord Injury (SCI) in Rats and Attenuates SCI-Induced Autophagy

Systemic Administration of Fibroblast Growth Factor 21 Improves the Recovery of Spinal Cord Injury (SCI) in Rats and Attenuates SCI-Induced Autophagy

Protecting the death of nerve cells is an essential tactic for spinal cord injury (SCI) repair. Recent studies show that nerve growth factors can reduce the death of nerve cells and promote the healing of nerve injury. To investigate the conducive effect of fibroblast growth factor 21 (FGF21) on SCI...

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Bibliographic Details
Main Authors: Sipin Zhu, Yibo Ying, Lin Ye, Weiyang Ying, Jiahui Ye, Qiuji Wu, Min Chen, Hui Zhu, Xiaoyang Li, Haicheng Dou, Huazi Xu, Zhouguang Wang, Jiake Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Pharmacology
Subjects:
spinal cord injury
fibroblast growth factor 21
autophagy
nerve regeneration
fibrotic scar
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.628369/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2020.628369/full

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