Urine colorimetry for therapeutic drug monitoring of pyrazinamide during tuberculosis treatment

Objectives: Pyrazinamide is a key drug in the first-line treatment regimen for tuberculosis, with a potent sterilizing effect. Although low pyrazinamide peak serum concentrations (Cmax) are associated with poor treatment outcomes, many resource-constrained settings do not have sufficient laboratory...

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Bibliographic Details
Main Authors: Isaac Zentner, Chawangwa Modongo, Nicola M. Zetola, Jotam G. Pasipanodya, Shashikant Srivastava, Scott K. Heysell, Stellah Mpagama, Hans P. Schlect, Tawanda Gumbo, Gregory P. Bisson, Christopher Vinnard
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:International Journal of Infectious Diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971217303296