Multiparametric analysis of cell-free DNA in melanoma patients.

Cell-free DNA in blood (cfDNA) represents a promising biomarker for cancer diagnosis. Total cfDNA concentration showed a scarce discriminatory power between patients and controls. A higher specificity in cancer diagnosis can be achieved by detecting tumor specific alterations in cfDNA, such as DNA i...

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Bibliographic Details
Main Authors: Francesca Salvianti, Pamela Pinzani, Paolo Verderio, Chiara Maura Ciniselli, Daniela Massi, Vincenzo De Giorgi, Marta Grazzini, Mario Pazzagli, Claudio Orlando
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3507877?pdf=render