Genetic regulation of alpha-synuclein mRNA expression in various human brain tissues.

Genetic regulation of alpha-synuclein mRNA expression in various human brain tissues.

Genetic variability across the SNCA locus has been repeatedly associated with susceptibility to sporadic Parkinson's disease (PD). Accumulated evidence emphasizes the importance of SNCA dosage and expression levels in PD pathogenesis. However whether genetic variability in the SNCA gene modulat...

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Bibliographic Details
Main Authors: Colton Linnertz, Laura Saucier, Dongliang Ge, Kenneth D Cronin, James R Burke, Jeffrey N Browndyke, Christine M Hulette, Kathleen A Welsh-Bohmer, Ornit Chiba-Falek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2759540?pdf=render

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http://europepmc.org/articles/PMC2759540?pdf=render

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