Infectivity of adeno-associated virus serotypes in mouse testis

Infectivity of adeno-associated virus serotypes in mouse testis

Abstract Background Recombinant adeno-associated viruses (AAVs) are emerging as favoured transgene delivery vectors for both research applications and gene therapy. In this context, a thorough investigation of the potential of various AAV serotypes to transduce specific cell types is valuable. Here,...

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Main Authors: Santhanasabapathy Rajasekaran, Jayashree Thatte, Jayaprakash Periasamy, Alok Javali, Manjunath Jayaram, Dwaipayan Sen, Akshaya Krishnagopal, Giridhara R. Jayandharan, Ramkumar Sambasivan
Format: Article
Language:English
Published: BMC 2018-11-01
Series:BMC Biotechnology
Subjects:
Adeno-associated viruses (AAV)
Germline transmission
Tropism
Mouse testis injection
Myoid cell
Leydig cell
Online Access:http://link.springer.com/article/10.1186/s12896-018-0479-1

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http://link.springer.com/article/10.1186/s12896-018-0479-1

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