Role of the phosphatase PTEN in early vascular remodeling.

BACKGROUND: The phosphatase PTEN represents an important physiological inhibitor of phosphatidylinositol-3 kinase (PI3-K)/protein kinase B (Akt) signalling, however, the functional role of PTEN in the initial phase of angioplasty-induced vascular injury remains elusive. In the present study we sough...

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Bibliographic Details
Main Authors: Daniel G Sedding, Rebecca Widmer-Teske, Andreas Mueller, Philipp Stieger, Jan-Marcus Daniel, Dursun Gündüz, Soni Pullamsetti, Holger Nef, Helge Moellmann, Christian Troidl, Christian Hamm, Rüdiger Braun-Dullaeus
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3606387?pdf=render