Expression signature of IFN/STAT1 signaling genes predicts poor survival outcome in glioblastoma multiforme in a subtype-specific manner.

Expression signature of IFN/STAT1 signaling genes predicts poor survival outcome in glioblastoma multiforme in a subtype-specific manner.

Previous reports have implicated an induction of genes in IFN/STAT1 (Interferon/STAT1) signaling in radiation resistant and prosurvival tumor phenotypes in a number of cancer cell lines, and we have hypothesized that upregulation of these genes may be predictive of poor survival outcome and/or treat...

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Bibliographic Details
Main Authors: Christine W Duarte, Christopher D Willey, Degui Zhi, Xiangqin Cui, Jacqueline J Harris, Laura Kelly Vaughan, Tapan Mehta, Raymond O McCubrey, Nikolai N Khodarev, Ralph R Weichselbaum, G Yancey Gillespie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3252343?pdf=render

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http://europepmc.org/articles/PMC3252343?pdf=render

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