The anti-HIV-1 activity of polyphenols from Phyllanthus urinaria and the pharmacokinetics and tissue distribution of its marker compound, gallic acid

Objective: To investigate the in vitro anti-HIV-1 activities and its associated mechanism of action of an extract isolated from Phyllanthus urinaria (P. urinaria) and to develop an HPLC test method for detecting gallic acid (GA) in plasma and tissues to study its pharmacokinetics and tissue distribu...

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Bibliographic Details
Main Authors: Xiaoxue Zhang, Qing Xia, Guanghui Yang, Dan Zhu, Yanyan Shao, Jiaying Zhang, Yaping Cui, Rufeng Wang, Lanzhen Zhang
Format: Article
Language:English
Published: Elsevier 2017-04-01
Series:Journal of Traditional Chinese Medical Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2095754816301545