Identification of positive and negative regulators in the stepwise developmental progression towards infectivity in Trypanosoma brucei

Abstract Trypanosoma brucei is a protozoan parasite that causes important human and livestock diseases in sub-Saharan Africa. By overexpressing a single RNA-binding protein, RBP6, in non-infectious procyclics trypanosomes, we previously recapitulated in vitro the events occurring in the tsetse fly v...

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Bibliographic Details
Main Authors: Justin Y. Toh, Agathe Nkouawa, Saúl Rojas Sánchez, Huafang Shi, Nikolay G. Kolev, Christian Tschudi
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-85225-2