Characterization of a reproducible model of fracture healing in mice using an open femoral osteotomy

Purpose: The classic fracture model, described by Bonnarens and Einhorn in 1984, enlists a blunt guillotine to generate a closed fracture in a pre-stabilized rodent femur. However, in less experienced hands, this technique yields considerable variability in fracture pattern and requires highly-speci...

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Bibliographic Details
Main Authors: C.D. Collier, B.S. Hausman, S.H. Zulqadar, E.S. Din, J.M. Anderson, O. Akkus, E.M. Greenfield
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Bone Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352187220300097