Preliminary Study of a 1,5-Benzodiazepine-Derivative Labelled with Indium-111 for CCK-2 Receptor Targeting

Preliminary Study of a 1,5-Benzodiazepine-Derivative Labelled with Indium-111 for CCK-2 Receptor Targeting

The cholecystokinin-2 receptor (CCK-2R) is overexpressed in several human cancers but displays limited expression in normal tissues. For this reason, it is a suitable target for developing specific radiotracers. In this study, a nastorazepide-based ligand functionalized with a 1,4,7,10-tetraazacyclo...

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Bibliographic Details
Main Authors: Marco Verona, Sara Rubagotti, Stefania Croci, Sophia Sarpaki, Francesca Borgna, Marianna Tosato, Elisa Vettorato, Giovanni Marzaro, Francesca Mastrotto, Mattia Asti
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Molecules
Subjects:
cholecystokinin-2 receptor
indium-111 labelling
nastorazepide
radiopharmaceuticals
Online Access:https://www.mdpi.com/1420-3049/26/4/918

Internet

https://www.mdpi.com/1420-3049/26/4/918

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