Ligand-Specific Regulation of the Endogenous Mu-Opioid Receptor by Chronic Treatment with Mu-Opioid Peptide Agonists

Ligand-Specific Regulation of the Endogenous Mu-Opioid Receptor by Chronic Treatment with Mu-Opioid Peptide Agonists

Since the discovery of the endomorphins (EM), the postulated endogenous peptide agonists of the mu-opioid receptors, several analogues have been synthesized to improve their binding and pharmacological profiles. We have shown previously that a new analogue, cis-1S,2R-aminocyclohexanecarboxylic acid2...

Full description

Bibliographic Details
Main Authors: Marianna Murányi, Resat Cinar, Orsolya Kékesi, Erika Birkás, Gabriella Fábián, Beáta Bozó, András Zentai, Géza Tóth, Emese Gabriella Kicsi, Mónika Mácsai, Roberta Dochnal, Gyula Szabó, Mária Szücs
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2013/501086

Internet

http://dx.doi.org/10.1155/2013/501086

Similar Items