Increased Immunogenicity of Full-Length Protein Antigens through Sortase-Mediated Coupling on the PapMV Vaccine Platform

<i>Background</i>: Flexuous rod-shape nanoparticles&#8212;made of the coat protein of papaya mosaic virus (PapMV)&#8212;provide a promising vaccine platform for the presentation of viral antigens to immune cells. The PapMV nanoparticles can be combined with viral antigens or cova...

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Bibliographic Details
Main Authors: Marie-Ève Laliberté-Gagné, Marilène Bolduc, Ariane Thérien, Caroline Garneau, Philippe Casault, Pierre Savard, Jérome Estaquier, Denis Leclerc
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/7/2/49