Cell alignment induced by anisotropic electrospun fibrous scaffolds alone has limited effect on cardiomyocyte maturation

Enhancing the maturation of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) will facilitate their applications in disease modeling and drug discovery. Previous studies suggest that cell alignment could enhance hPSC-CM maturation; however, the robustness of this approach has not been we...

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Bibliographic Details
Main Authors: Jingjia Han, Qingling Wu, Younan Xia, Mary B. Wagner, Chunhui Xu
Format: Article
Language:English
Published: Elsevier 2016-05-01
Series:Stem Cell Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S187350611630023X