Sub-ohm vaping increases the levels of carbonyls, is cytotoxic, and alters gene expression in human bronchial epithelial cells exposed at the air–liquid interface

Abstract Background Exposure to electronic-cigarette (e-cig) aerosols induces potentially fatal e-cig or vaping-associated lung injury (EVALI). The cellular and molecular mechanisms underlying these effects, however, are unknown. We used an air–liquid interface (ALI) in vitro model to determine the...

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Bibliographic Details
Main Authors: Alexandra Noël, Ekhtear Hossain, Zakia Perveen, Hasan Zaman, Arthur L. Penn
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Respiratory Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12931-020-01571-1