Conditional Knockout of Src Homology 2 Domain-containing Protein Tyrosine Phosphatase-2 in Myeloid Cells Attenuates Renal Fibrosis after Unilateral Ureter Obstruction

Conditional Knockout of Src Homology 2 Domain-containing Protein Tyrosine Phosphatase-2 in Myeloid Cells Attenuates Renal Fibrosis after Unilateral Ureter Obstruction

Background: Src homology 2 domain-containing protein tyrosine phosphatase-2 (SHP-2) is a kind of intracellular protein tyrosine phosphatase. Studies have revealed its roles in various disease, however, whether SHP-2 involves in renal fibrosis remains unclear. The aim of this study was to explore the...

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Bibliographic Details
Main Authors: Jing-Fei Teng, Kai Wang, Yao Li, Fa-Jun Qu, Qing Yuan, Xin-Gang Cui, Quan-Xing Wang, Dan-Feng Xu
Format: Article
Language:English
Published: Wolters Kluwer 2015-01-01
Series:Chinese Medical Journal
Subjects:
Fibrosis; Inflammation; Myeloid Cells; Obstructive Nephropathy; Src Homology 2 Domain-Containing Protein Tyrosine Phosphatase-2
Online Access:http://www.cmj.org/article.asp?issn=0366-6999;year=2015;volume=128;issue=9;spage=1196;epage=1201;aulast=Teng

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http://www.cmj.org/article.asp?issn=0366-6999;year=2015;volume=128;issue=9;spage=1196;epage=1201;aulast=Teng

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