Local tertiary structure probing of ribonucleoprotein particles by nuclease fusion proteins.

Analyses of the conformational dynamics of the numerous cellular ribonucleoprotein particles (RNP) significantly contribute to the understanding of their modes of action. Here, we tested whether ribonuclease fusion proteins incorporated into RNPs can be used as molecular probes to characterize the l...

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Bibliographic Details
Main Authors: Uli Ohmayer, Jorge Perez-Fernandez, Thomas Hierlmeier, Gisela Pöll, Lydia Williams, Joachim Griesenbeck, Herbert Tschochner, Philipp Milkereit
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22876323/?tool=EBI