MIR22HG acts as a tumor suppressor via TGFβ/SMAD signaling and facilitates immunotherapy in colorectal cancer

MIR22HG acts as a tumor suppressor via TGFβ/SMAD signaling and facilitates immunotherapy in colorectal cancer

Abstract Background Long noncoding RNAs (lncRNAs) are emerging as critical regulatory elements and play fundamental roles in the biology of various cancers. However, we are still lack of knowledge about their expression patterns and functions in human colorectal cancer (CRC). Methods Differentially...

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Bibliographic Details
Main Authors: Juan Xu, Tingting Shao, Mingxu Song, Yunjin Xie, Jialiang Zhou, Jiaqi Yin, Na Ding, Haozhe Zou, Yongsheng Li, Jiwei Zhang
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Molecular Cancer
Subjects:
MIR22HG
TGFβ pathway
Colorectal cancer
Immunotherapy
SMAD2
Online Access:http://link.springer.com/article/10.1186/s12943-020-01174-w

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http://link.springer.com/article/10.1186/s12943-020-01174-w

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