The contribution of N2O3 to the cytotoxicity of the nitric oxide donor DETA/NO: an emerging role for S-nitrosylation

The contribution of N2O3 to the cytotoxicity of the nitric oxide donor DETA/NO: an emerging role for S-nitrosylation

The relationship between the biological activity of NO and its chemistry is complex. The objectives of this study were to investigate the influence of oxygen tension on the cytotoxicity of the NO• donor DETA/NO and to determine the effects of oxygen tension on the key RNS (reactive nitrog...

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Bibliographic Details
Main Authors: Ahlam A. Ali, Jonathan A. Coulter, Claire H. Ogle, Marie M. Migaud, David G. Hirst, Tracy Robson, Helen O. McCarthy
Format: Article
Language:English
Published: Portland Press, Biochemical Society 2013-03-01
Series:Bioscience Reports
Subjects:
cytotoxicity
hypoxia
nitric oxide
S-nitrosylation
Online Access:http://www.bioscirep.org/bsr/033/e031/bsr033e031.htm

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http://www.bioscirep.org/bsr/033/e031/bsr033e031.htm

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