Human adipose-tissue derived stromal cells in combination with hypoxia effectively support ex vivo expansion of cord blood haematopoietic progenitors.

Human adipose-tissue derived stromal cells in combination with hypoxia effectively support ex vivo expansion of cord blood haematopoietic progenitors.

The optimisation of haematopoietic stem and progenitor cell expansion is on demand in modern cell therapy. In this work, haematopoietic stem/progenitor cells (HSPCs) have been selected from unmanipulated cord blood mononuclear cells (cbMNCs) due to adhesion to human adipose-tissue derived stromal ce...

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Bibliographic Details
Main Authors: Elena R Andreeva, Irina V Andrianova, Elena V Sotnezova, Sergey V Buravkov, Polina I Bobyleva, Yury A Romanov, Ludmila B Buravkova
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4412539?pdf=render

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http://europepmc.org/articles/PMC4412539?pdf=render

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