DNA Methylation Profile in Human Cord Blood Mononuclear Leukocytes From Term Neonates: Effects of Histological Chorioamnionitis

DNA Methylation Profile in Human Cord Blood Mononuclear Leukocytes From Term Neonates: Effects of Histological Chorioamnionitis

Background: Histological chorioamnionitis (HCA) is an infection/inflammation of fetal membranes and complicates 5.2–28.5% of all live births. Exposure to HCA can have long-term consequences including abnormal neurodevelopment and an increased risk for allergic disorders and asthma later in childhood...

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Bibliographic Details
Main Authors: Gina Fong, Suhita Gayen nee' Betal, Swati Murthy, Michael Favara, Joanna S. Y. Chan, Sankar Addya, Thomas H. Shaffer, Jay Greenspan, Vineet Bhandari, Dongmei Li, Irfan Rahman, Zubair H. Aghai
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Pediatrics
Subjects:
epigenetics
leukocytes
histological chorioamnionitis
differential DNA methylation
immune modulation
Online Access:https://www.frontiersin.org/article/10.3389/fped.2020.00437/full

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https://www.frontiersin.org/article/10.3389/fped.2020.00437/full

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