Coordinate regulation of mature dopaminergic axon morphology by macroautophagy and the PTEN signaling pathway.

Coordinate regulation of mature dopaminergic axon morphology by macroautophagy and the PTEN signaling pathway.

Macroautophagy is a conserved mechanism for the bulk degradation of proteins and organelles. Pathological studies have implicated defective macroautophagy in neurodegeneration, but physiological functions of macroautophagy in adult neurons remain unclear. Here we show that Atg7, an essential macroau...

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Bibliographic Details
Main Authors: Keiichi Inoue, Joanne Rispoli, Lichuan Yang, David Macleod, M Flint Beal, Eric Klann, Asa Abeliovich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3789823?pdf=render

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http://europepmc.org/articles/PMC3789823?pdf=render

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