Effects of age and parity on mammary gland lesions and progenitor cells in the FVB/N-RC mice.

The FVB/N mouse strain is extensively used in the development of animal models for breast cancer research. Recently it has been reported that the aging FVB/N mice develop spontaneous mammary lesions and tumors accompanied with abnormalities in the pituitary glands. These observations have a great im...

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Bibliographic Details
Main Authors: Ahmed Raafat, Luigi Strizzi, Karim Lashin, Erika Ginsburg, David McCurdy, David Salomon, Gilbert H Smith, Daniel Medina, Robert Callahan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3431359?pdf=render