FlexiBAC: a versatile, open-source baculovirus vector system for protein expression, secretion, and proteolytic processing

FlexiBAC: a versatile, open-source baculovirus vector system for protein expression, secretion, and proteolytic processing

Abstract Background Baculovirus-mediated expression in insect cells is a powerful approach for protein production. However, many existing methods are time-consuming, offer limited options for protein tagging, and are unsuitable for secreted proteins requiring proteolytic maturation, such as TGF-β fa...

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Bibliographic Details
Main Authors: Régis P. Lemaitre, Aliona Bogdanova, Barbara Borgonovo, Jeffrey B. Woodruff, David N. Drechsel
Format: Article
Language:English
Published: BMC 2019-03-01
Series:BMC Biotechnology
Subjects:
Baculovirus
Intrinsically disordered proteins
Protein expression
TGF-β
Online Access:http://link.springer.com/article/10.1186/s12896-019-0512-z

Internet

http://link.springer.com/article/10.1186/s12896-019-0512-z

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