Candidate gene study of TRAIL and TRAIL receptors: association with response to interferon beta therapy in multiple sclerosis patients.

TRAIL and TRAIL Receptor genes have been implicated in Multiple Sclerosis pathology as well as in the response to IFN beta therapy. The objective of our study was to evaluate the association of these genes in relation to the age at disease onset (AAO) and to the clinical response upon IFN beta treat...

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Main Authors: Carlos López-Gómez, Almudena Pino-Ángeles, Teresa Órpez-Zafra, María Jesús Pinto-Medel, Begoña Oliver-Martos, Jesús Ortega-Pinazo, Carlos Arnáiz, Cristina Guijarro-Castro, Jezabel Varadé, Roberto Álvarez-Lafuente, Elena Urcelay, Francisca Sánchez-Jiménez, Óscar Fernández, Laura Leyva
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3639207?pdf=render