Association between changes in molecular biomarkers of cartilage matrix turnover and changes in knee articular cartilage: a longitudinal pilot study

Abstract Background An early detection of Osteoarthritis is urgently needed and still not possible until today. The aim of the study was to assess whether molecular biomarkers of cartilage turnover are associated with longitudinal change in knee cartilage thickness during a 2 year period in individu...

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Bibliographic Details
Main Authors: Heide Boeth, Peter C. Raffalt, Aoife MacMahon, A. Robin Poole, Felix Eckstein, Wolfgang Wirth, Frank Buttgereit, Patrik Önnerfjord, Pilar Lorenzo, Cecilia Klint, Anna Pramhed, Georg N. Duda
Format: Article
Language:English
Published: SpringerOpen 2019-05-01
Series:Journal of Experimental Orthopaedics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40634-019-0179-3