Selection of target mutation in rat gastrointestinal tract E. coli by very low concentration of fluoroquinolone

It has been suggested that bacterial resistance is selected within a mutation selection window of antibiotics. More recent studies showed that even extremely low concentration of antibiotic could select resistant bacteria in vitro. Yet little is known about the exact antibiotic concentration range t...

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Bibliographic Details
Main Authors: Dachuan eLin, Kaichao eChen, Ruichao eLi, Jiubiao eGuo, Wen eYao, Sheng eChen
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-09-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00468/full