Small Interfering RNA Specific for N-Methyl-D-Aspartate Receptor 2B Offers Neuroprotection to Dopamine Neurons through Activation of MAP Kinase

In the present study, N-methyl-D-aspartate receptor 2B (NR2B)-specific siRNA was applied in parkinsonian models. Our previous results showed that reduction in expression of N-methyl-D-aspartate receptor 1 (NR1), the key subunit of N-methyl-D-aspartate receptors, by antisense oligos amelio-rated the...

Full description

Bibliographic Details
Main Authors: Olivia T.W. Ng, L.W. Chen, Y.S. Chan, Ken K.L. Yung
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2012-02-01
Series:Neurosignals
Subjects:
Online Access:http://www.karger.com/Article/FullText/334720