In Situ Microparticles Loaded with S-Nitrosoglutathione Protect from Stroke.

Treatment of stroke, especially during the first hours or days, is still lacking. S-nitrosoglutathione (GSNO), a cerebroprotective agent with short life time, may help if administered early with a sustain delivery while avoiding intensive reduction in blood pressure. We developed in situ forming imp...

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Bibliographic Details
Main Authors: Marianne Parent, Ariane Boudier, Julien Perrin, Claude Vigneron, Philippe Maincent, Nicolas Violle, Jean-François Bisson, Isabelle Lartaud, François Dupuis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4672927?pdf=render