Prolonged Pseudohypoxia Targets Ambra1 mRNA to P-Bodies for Translational Repression.

Hypoxia has been associated with several pathological conditions ranging from stroke to cancer. This condition results in the activation of autophagy, a cyto-protective response involving the formation of double-membraned structures, the autophagosomes, in the cytoplasm. In this study, we investigat...

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Bibliographic Details
Main Authors: Somayeh Pourpirali, Cristina Valacca, Paola Merlo, Salvatore Rizza, Silvia D'Amico, Francesco Cecconi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4473010?pdf=render