KDM5B decommissions the H3K4 methylation landscape of self-renewal genes during trophoblast stem cell differentiation

Trophoblast stem (TS) cells derived from the trophectoderm (TE) of mammalian embryos have the ability to self-renew indefinitely or differentiate into fetal lineages of the placenta. Epigenetic control of gene expression plays an instrumental role in dictating the fate of TS cell self-renewal and di...

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Bibliographic Details
Main Authors: Jian Xu, Benjamin L. Kidder
Format: Article
Language:English
Published: The Company of Biologists 2018-05-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/7/5/bio031245