pMHC Structural Comparisons as a Pivotal Element to Detect and Validate T-Cell Targets for Vaccine Development and Immunotherapy—A New Methodological Proposal

The search for epitopes that will effectively trigger an immune response remains the “El Dorado” for immunologists. The development of promising immunotherapeutic approaches requires the appropriate targets to elicit a proper immune response. Considering the high degree of HLA/TC...

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Bibliographic Details
Main Authors: Priscila Vianna, Marcus F.A. Mendes, Marcelo A. Bragatte, Priscila S. Ferreira, Francisco M. Salzano, Martin H. Bonamino, Gustavo F. Vieira
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/8/12/1488